N4 Ch 13 MedSurg Qs on Immune Responses

1. If a person is heterozygous for a given gene, it means that the person
A. is a carrier for a genetic disorder.
B. is affected by the genetic disorder.
C. has two identical alleles for the gene.
D. has two different alleles for the gene.

2. A father who has a sex-linked recessive disorder and a wife with a normal genotype will
A. pass the carrier state to his male children.
B. pass the carrier state to all of his children.
C. pass the carrier state to his female children.
D. not pass on the genetic mutation to any of his children.

3. The function of monocytes in immunity is related to their ability to
A. stimulate the production of T and B lymphocytes.
B. produce antibodies on exposure to foreign substances.
C. bind antigens and stimulate natural killer cell activation.
D. capture antigens by phagocytosis and present them to lymphocytes.

4. One function of cell-mediated immunity is
A. formation of antibodies.
B. activation of the complement system.
C. surveillance for malignant cell changes.
D. opsonization of antigens to allow phagocytosis by neutrophils.

5. The reason newborns are protected for the first 6 months of life from bacterial infections is because of the maternal transmission of
A. IgG.
B. IgA.
C. IgM.
D. IgE.

6. In a type I hypersensitivity reaction, the primary immunologic disorder appears to be
A. binding of IgG to an antigen on a cell surface.
B. deposit of antigen-antibody complexes in small vessels.
C. release of lymphokines to interact with specific antigens.
D. release of chemical mediators from IgE-bound mast cells and basophils.

7. The nurse is alerted to possible anaphylactic shock immediately after a patient has received intramuscular penicillin by the development of
A. edema and itching at the injection site.
B. sneezing and itching of the nose and eyes.
C. a wheal-and-flare reaction at the injection site.
D. chest tightness and production of thick sputum.

8. The nurse advises a friend who asks him to administer his allergy shots that
A. it is illegal for nurses to administer injections outside of a medical setting.
B. he is qualified to do it if the friend has epinephrine in an injectible syringe provided with his extract.
C. avoiding the allergens is a more effective way of controlling allergies and allergy shots are not usually effective.
D. immunotherapy should only be administered in a setting where emergency equipment and drugs are available.

9. A patient is undergoing plasmapheresis for treatment of systemic lupus erythematosus. The nurse explains that plasmapheresis is used in her treatment to
A. remove T lymphocytes in her blood that are producing antinuclear antibodies.
B. remove normal particles in her blood that are being damaged by autoantibodies.
C. exchange her plasma that contains antinuclear antibodies with a substitute fluid.
D. replace viral-damaged cellular components of her blood with replacement whole blood.

10. Association between HLA antigens and diseases is most commonly found in what disease conditions?
A. malignancies
B. infectious diseases
C. neurologic diseases
D. autoimmune disorders

11. The most common cause of secondary immunodeficiencies is
A. drugs.
B. stress.
C. malnutrition.
D. human immunodeficiency virus.

12. If a person is having an acute rejection of a transplanted organ, which of the following drugs would most likely be used?
A. tacrolimus
B. cyclosporine
C. muromonab-CD3
D. mycophenolate mofetil

13.
Which of the following techniques can be used to modify an individual’s genetic structure?
A. gene therapy
B. polymerase chain reaction
C. recombinant RNA technology
D. monoclonal antibody production