Drug Practice

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1. When administering chemotherapy, the nurse should be aware of which of the following interactions?
a. Cytotoxic chemotherapy drugs should never be given concurrently with another drug.
b.Drug interactions can result in additive toxicity, decreased effectiveness, or altered activity of non-chemotherapeutic medications.
c. Chemotherapy should never be administered in sequence with another drug.
d. The number of drugs a client is taking does not influence the incidence of drug interactions.

2. The nurse assesses for cardiotoxicity most carefully in a client receiving which of the following chemotherapeutic agents?
a. Vincristine (Oncovin)
b. Doxorubicin (Adriamycin)
c. Nitrogen mustard (Mustargen)
d. Cisplatin (Platinol)

3. When administering vesicant chemotherapy to a client, the nurse should do which of the following?
a. Instruct the client to report any pain or burning experienced during infusion.
b. Infuse this type of meication in the large veins of the hands or wrist.
c. Assess for a blood return after each 5 to 10 mL of chemotherapeutic drug administered.
d. Apply a warm compress during the infusion ro dilate the vein.

4. A client asks the nurse to explain the term "cell cycle specific," which was overheard when the health care team made rounds. The nurse replies that chemotherapy drugs that are cell cycle specific act preferentially on cells that:
a. Are well developed.
b. Have entered a resting phase and are not growing.
c. Are actively getting ready to divide or are dividing.
d. Are no longer alive.

5. Which of the following is the initial step that the nurse takes in client and family education regarding chemotherapy administration?
a. Clarify information and dispel misconceptions.
b. Obtain informed consent.
c. Choose an appropriate venous access.
d. Demonstrate safe gloving and gowning.

6. The nurse places highest priority on assessing for which of the following most common and most lethal side effect of chemotherapy?
a. Increased respiratory rate.
b. Electrolyte imbalance.
c. Myleosuppression.
d. Elevated liver function studies.

7. After noting altered gait, altered reflexes, and ileus in a client receiving chemotherapy, the nurse would report to the oncologist that which of the following types of organ damage is occuring?
a. Hepatic.
b. Neurologic.
c. Renal.
d. Gastrointestinal.

8. The nurse is especially careful to assess for hematuria and dysuria when a client is receiving which of the following chemotherapeutic agents?
a. Cyclophosphamide (Cytoxan)
b. Doxorubican (Adriamycin)
c. Fluorouracil (5-FU)
d. Cytarabine (Ara-C)

9. Which of the following interventions represents the best nursing action should an extravasation of a vesicant occur?
a. The infusion of the drug should be stopped and a new site chosen for administration.
b. The site should be treated with appropriate antidote and observed for 3to 4 weeks.
c. A plastic surgeon should be consulted immediately.
d. Emergency medical care, in cluding corticosteroids and epinephrine, should be administered immediately.

10. The nurse reinforcing health teaching with a client explains that dose limitations of chemotherapy are determined by which of the following client or drug related factors?
a. Physical staus and medical history.
b. History of previous treatments.
c. Number od cancer cells in the body.
d. The toxicities of a particular drug.