N4 - Test - Lymphoma and Leukemia

Answers in comments.
Lymphoma - Hodgkin's disease and non-Hodgkin's

Hodgkins - Multinucleated cells (Reed Sternburg)- usually young - Predictable growth - Radiation - Chemo - Both - The standard chemo regimen, known as ABVD, includes
A-adriamycin (doxorubicin), B-bleomycin, V-vinblastine, and D-dacarbazine.
(Prevent pregnancy and bank sperm and ova cells if you want kids later, wait 2 years post tx)
Non-Hodgkins - Unpredictable growth - Any age - Radiation - Chemo - Both - B or T cells in lymph system - CHOP-R chemotherapy ( C-cyclophosphamide, H-hydroxydaunomycin,
O-oncovin [vincristine], P-prednisone, and R-rituximab)
Fast growing-Pt. presents sicker, earlier-easier cure
Slow growing-Pt. presents later, watch and wait , Tx when symptoms show- not as good prognosis

Staging Hodgkin's and non-Hodgkin's
Stage I single lymph node or localized
Stage II two or more nodes - same side of diaphragm
Stage III several nodes- both sides diaphragm
Stage IV outside lymph tissue ( bone marrow)

Leukemia
Bone marrow biopsy for Dx
Acute myelogenous leukemia (AML) most acute leukemias in adults
Acute lymphocytic leukemia (ALL) more common in children.
Chronic myelogenous leukemia (CML) typically strikes between ages 40 and 50, more men than women.
Chronic lymphocytic leukemia (CLL) usually after 40, most common in older men.

autologous - self
human-leukocyte-antigen (HLA) matched and related
unrelated donor (allogeneic)

http://www.nursingcenter.com/library/journalarticle.asp?article_id=591039

1.
Which of the following accurately describes lymphoma?
a. any type of liquid tumor
b. malignant tissue within the lymph nodes
c. benign or malignant lymph node tumors
d. malignancy of the lymphocytes producing tumors in lymphoid tissue

2.
Fatigue, weight loss, fever, and night sweats are signs and symptoms of
a. Hodgkin's disease only.
b. NHL only.
c. both Hodgkin's disease and NHL.
d. neither Hodgkin's disease nor NHL.

3.
Lymphoma involving two or more lymph node regions on the same side of the diaphragm is
a. stage I.
b. stage II.
c. stage III.
d. stage IV.

4.
Which symptoms and treatment are most likely for a 23-year-old woman with stage IA Hodgkin's disease?
a. asymptomatic, radiation therapy only
b. asymptomatic, radiation and chemotherapy
c. fever and night sweats, radiation therapy only
d. fever and night sweats, radiation and chemotherapy

5.
Which of the following tests are done to stage lymphoma?
a. pulmonary function tests and chest X-ray
b. lymph node biopsies and a CT scan
c. DNA testing for the Philadelphia chromosome
d. chest X-ray, CT and PET scans, and bone marrow biopsy

6.
What's the standard treatment regimen for advanced Hodgkin's disease?
a. ABVD
b. ASCT
c. CHOP
d. MOPP

7.
The purpose of administering rituximab for NHL is to
a. combat infections.
b. enhance the effects of chemotherapy.
c. increase circulating monocytes.
d. prevent complications associated with chemotherapy.

8.
Anthracyclines used to treat leukemias and lymphomas are
a. anticancer antibiotics, such as doxorubicin.
b. tyrosine kinase inhibitors, such as imatinib.
c. monoclonal antibodies, such as rituximab.
d. vesicants, such as vincristine.

9.
Which of the following cells are normally found in the blood?
a. blasts
b. bands
c. myelocytes
d. stem cells

10.
Stem cells for an allogeneic bone marrow transplant are obtained from
a. the patient.
b. an HLA-matched donor.
c. an HLA-unmatched donor.
d. cloned stem cell colonies.

11.
Which type of leukemia is most likely in a 10-year-old child?
a. ALL
b. CLL
c. AML
d. CML

12.
The signs and symptoms of leukemia are caused by
a. abnormally high levels of circulating mature WBCs.
b. abnormally high levels of circulating mature lymphocytes.
c. circulating promyelocytes, myelocytes, and metamyelocytes.
d. circulating immature RBCs, WBCs, and platelets.

13.
Bleeding and easy bruising associated with leukemia are due to
a. thrombocytopenia.
b. leukopenia.
c. thrombocytosis.
d. leukocytosis.

14.
What are the phases of CML?
a. acute and chronic
b. indolent and aggressive
c. chronic, accelerated, and blast
d. induction, consolidation, and proliferation

15.
Teach a patient whose chemotherapy is associated with cystitis to
a. take a diuretic before the infusion.
b. restrict oral fluid intake.
c. test his urine for protein and acetone.
d. void frequently.