N4 quiz Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Price: Pathophysiology, 6th Edition
Study Questions Chapter 72

1.
In SLE, women are affected approximately how many times more than are men?
A.5
B.7
C.8
D.10

2.
The most common initial manifestation of SLE is:
A.Symmetric arthritis or arthralgia
B.Subcutaneous nodules
C.Fatigue and weakness
D.Weight loss

3.
Which of the following laboratory tests will be positive in greater than 95% of patients with SLE?
A.ANA
B.Increased serum complement levels
C.Decreased erythrocyte sedimentation rate
D.Positive rheumatoid factor

4.
The serial or simultaneous presence of which of the criteria listed below is considered diagnostic of SLE?
A.Photosensitivity, positive ANA test, symmetric joint swelling, subcutaneous nodules
B.Malar rash, pain on motion, morning stiffness lasting less than 30 minutes, ulcers
C.Photosensitivity, malar rash, positive ANA test, hemolytic anemia
D.Photosensitivity, positive rheumatoid factor, oral ulcers, pleuritis

5.
The formation of antibodies against which of the following antigens is considered diagnostic of SLE?
A.Membrane protein
B.IgM
C.dsDNA
D.RNA

6.
Which of the following drugs are able to induce a syndrome (symptoms of SLE) that is similar to SLE? (More than one answer may be correct.)
A.Isoniazid
B.Procainamide
C.Hydralazine
D.Chlorpromazine

7.
Drug therapy for SLE generally includes: (More than one answer may be correct.)
A.Corticosteroids
B.NSAIDs
C.Immunosuppressive agents
D.Cytotoxic drugs

8.
The onset of SLE is most frequently seen in late adolescence or early adulthood.
TrueFalse

9.
Cyclophosphamide or azathioprine is prescribed for SLE to control the symptoms and achieve a remission.
TrueFalse

10.
Lupus nephritis is a serious disorder that occurs in more than 80% of the individuals with SLE.
TrueFalse

11.
DNA is not usually antigenic to humans with SLE.
TrueFalse

12.
Antibodies to dsDNA and to RNA-protein complex termed Sm are only in SLE patients.
TrueFalse